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A new chimerism analysis based on automated interphase fluorescence in situ hybridization FISH evaluation was established to detect residual cells after allogene sex-mismatched bone marrow or blood stem-cell transplantation. The automatic slide scanning platform Metafer with its module MetaCyte was used to analyse 3, cells per sample. As to be expected, patients of the latter group were associated with a higher survival rate 48 vs. In only two of seven patients with disease-marker positive residual cells between 0. Besides, disease-marker negative residual cells were found in two patients without relapse at a rate of 2. Overall, with the presented automatic chimerism analysis of interphase FISH slides, a sensitive method for detection of disease-marker positive residual cells is on hand. Please select your country of residence.
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